In early February 2026, the U.S. District Court for the District of Delaware denied Moderna’s bid for summary judgment in a ...

Researchers developed a simulation showing how lipid nanoparticles release mRNA in acidic endosomes. The study reveals how ...

From vaccines to personalized cancer therapies, scientists are studying the use of mRNA across many clinical applications. However, there are several factors that are unique to mRNA drug product ...

A study from FAU has shown that lipid nanoparticles restructure their membrane significantly after being absorbed into a cell ...

The modified lipid nanoparticle (CDL-LNP) contains several ingredients that work together to deliver mRNA effectively: the mRNA payload with genetic instructions, standard lipid molecules (ionizable ...

Behind the household COVID-19 name, Moderna, is facing a $5 billion patent-infringement lawsuit over vaccine technology. On ...

When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether the mRNA ...

A new material could significantly improve the delivery and effectiveness of mRNA vaccines by replacing a commonly used ingredient that may trigger unwanted immune responses in some people. (Nanowerk ...

Researchers at Nagoya University in Japan have developed a lipid nanoparticle that delivers mRNA to cells five times more effectively. By attaching a sulfur-containing ring structure—a cyclic ...